By Christopher P. Dufault, P.AG., and Robert Saik, P.AG. CAC
These days we are exposed to a great deal of negative, one-sided and inaccurate information in the media and online about a herbicide called gylphosate, often sold under the trade name Roundup.
We interact with farmers and farm organizations on a regular basis. We understand their concerns with economic sustainability and their interest in environmental stewardship. And we understand the valuable contribution that technological advances have made in improving the sustainability of agriculture. Now, agenda-driven groups seek to take one of agriculture’s most useful technologies, glyphosate, and end its use through well- orchestrated, alarmist misinformation campaigns.
But what do government surveys and regulatory decisions tell us? To understand the real story we turn to an excellent set of data that tracks trends in pesticide use, hazard and risk, over time from the Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA) in Ontario, Canada. This data, collected using consistent methodology, enables us to learn more about how changing farming practices impact the environment and those working in agriculture.
In this article we’ll talk about:
- the overall reduction in the amount of herbicide applied in Ontario corn and soybean production;
- the increased use of glyphosate and benefits versus other herbicides displaced by glyphosate;
- the reduced hazard and risk from the use of glyphosate, based on indicators called the environmental impact quotient (EIQ) and environmental impact (EI), respectively; and
- the positive reassessments of the safety of glyphosate by the world’s major pesticide regulators.
USE OF HERBICIDES INCLUDING GLYPHOSATE IN ONTARIO
Every five years, for the past several decades, Ontario has surveyed farmers on their use of pesticides including herbicides, insecticides and fungicides. The most recent survey dates from 2013-2014 (1). Today, we are focusing on what this survey tells us about trends in the use of herbicides in corn and soybeans in Ontario.
Between 1983 and 2013, the total amount of herbicide used in field corn in Ontario declined by 39% (Figure 1). This reduction is primarily due to the increased use of glyphosate, which is applied at a lower rate of active ingredient (ai) per acre than the herbicides it replaced, increasing from 1% to 54% of the amount of all herbicides applied to field corn during that period. Furthermore, the decline in the total amount of herbicide applied occurred despite an 11% increase in the area grown to field corn (Figure 1).
In that same 30-year period, the yield per acre of field corn increased by 74% (Figure 2). And due to a combination of the reduced amount of herbicide applied per acre and increased yield, the amount of kg ai of all herbicides applied per bushel produced declined by a whopping 70% (Figure 2).
Soybeans are also a good news story. Between 1983 and 2013, despite the acreage of soybean grown in Ontario increasing by a massive 188%, the total amount of herbicide applied increased by just 47% (Figure 3). As with field corn, this is largely due to the replacement, by glyphosate, of other higher-rate herbicides; usage of glyphosate increased from 2% to 82% of all herbicides applied during that time frame (Figure 3).
In that same 30-year period, the yield of soybean increased by 53% (Figure 4). And the amount of kg ai of all herbicides applied per bushel produced declined by an impressive 67% (Figure 4).
AGRONOMIC BENEFITS OF GLYPHOSATE
From an agronomic perspective, glyphosate has been referred to as a “once-in-a-century herbicide” (2). Being a broad-spectrum herbicide, it controls virtually all species of weeds and has been utilized mostly in conjunction with herbicide-tolerant crops since their first appearance in the mid-1990s. Glyphosate also largely eliminates the need for several applications of multiple limited-spectrum herbicide active ingredients that would otherwise be needed to control all the species of weeds present. Not only do these other herbicides generally have higher hazard/risk profiles (discussed below), but they are often more phytotoxic. The resultant crop damage reduces yields unlike when glyphosate is used in herbicide-tolerant crops. Economists have estimated that if the world ceased to grow genetically-modified herbicide-tolerant crops in the absence of glyphosate, the annual loss of farm income would be $6.76 billion and there would be substantial declines in the production of soybean, corn and canola (3).
The widespread adoption of glyphosate has also resulted in decreased tillage (or soil cultivation) as farmers have adopted minimum or zero tillage growing systems. This has profound implications because reduced tillage means lower greenhouse gas emissions from burning less fossil fuel as well as from reduced decomposition of organic matter in the soil. Additionally, the associated increase in soil tilth brings better water holding capacity and increased soil health.
ENVIRONMENTAL IMPACT QUOTIENT (EIQ) AND ENVIRONMENTAL IMPACT (EI) OF GLYPHOSATE
Based on the data just cited, it is apparent that the amount of herbicide used to produce field corn and soybeans in Ontario has declined due to glyphosate largely replacing other major herbicides that are applied at higher rates. But, does a lower rate of application also mean reduced risk?
In conjunction with the results of the pesticide use survey, Ontario also published a report on the environmental risk associated with pesticide use in Ontario (4). This report used an Environmental Impact Quotient (EIQ) to estimate the hazard associated with the use of each pesticide recorded in the survey. Essentially, the EIQ is an indicator of the potential of a pesticide to cause harm. The EIQs for different pesticides can be compared and the higher the EIQ value, the greater the possible harm such as to farm workers, consumers and ecosystems.
Different way of calculating an EIQ are found in the published literature. The particular EIQ used by Ontario in this study is calculated based on data taken from 12 different data points from safety tests conducted on pesticides in the laboratory and the field. Briefly, these include measures of short- and long-term toxicity in laboratory animals, half-life, whether systemic in plants (i.e., tendency to circulate through plant tissues), leaching and runoff potential, and toxicity to several species of non-target animals.
The reported EIQ for glyphosate was calculated to be just 15.3 which is the tenth lowest EIQ of all the pesticide active ingredients from the survey. Furthermore, glyphosate has partially replaced the use of herbicides with higher EIQs, including atrazine (EIQ = 22.9) in corn, and metolachlor/s-metolachlor (EIQ = 22.0) in corn and soybeans, meaning it is less hazardous than these herbicides. This low EIQ for glyphosate is not surprising, considering that it is “less acutely toxic than common chemicals such as sodium chloride (salt) or aspirin” (2).
So, what about risk? This can be called environmental impact (EI) and is essentially hazard (EIQ) multiplied by exposure (i.e., amount used). Not only does glyphosate have a lower EIQ than the above-mentioned major herbicides that it replaces, but it is also recommended in Ontario for application at a lower rate per acre than the other herbicides when applied on their own (5). Whereas, the Ontario study (4) calculated EIs for the use of glyphosate in the whole province, we have done so on a per acre basis. The combination of factors – lower EIQ and lower rate – means the EI for glyphosate per acre of field corn, for example, is about 60% less than for the major herbicides that it replaces (Figure 5).
REGULATORY STATUS OF GLYPHOSATE
So, all the above is good news for producers and the environment. But it’s fair to say that the 12 data points used in estimating the EIQ are taken from a fraction of all the health and environmental studies done to assess the safety of pesticides. And, there’s the 2015 report from the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO) that classified glyphosate as “probably carcinogenic to humans” (6).
This report has engendered much controversy as evidenced by the many, contrasting points of view on the subject that can be found on the internet. We will simply say the following:
- The IARC report took account only of published toxicity data on glyphosate.
- The IARC report was a hazard assessment that would take account of how glyphosate is used. Remember hazard x exposure = risk.
- The pesticide regulators in each country in which glyphosate is registered have access to much more substantial and relevant data sets than does IARC. For example, in addition to reviewing and validating published data, these organizations also review the extensive body of toxicology studies from registrants that are conducted using internationally- accepted protocols. These latter studies are also required to meet stringent Good Laboratory Practice (GLP) guidelines such as those of the Organization for Economic Co- operation and Development (OECD) (7).
- Regulatory agencies update their reviews of all registered pesticides at regular intervals; Canada and the USA do so every 15 years. And virtually all the pesticide regulatory agencies in the world, that have recently updated their reviews of glyphosate, have reconfirmed its safety and renewed its registration, in contrast to IARC’s assessment of glyphosate as being “probably carcinogenic to humans.”
Here’s a small sampling of what some of these regulatory agencies have published:
- In March 2017, the European Chemicals Agency reported their determination that glyphosate is not classified as a carcinogen (8).
- In its draft “Revised Glyphosate Issue Paper: Evaluation of Carcinogenic Potential” document for public comment dated December 12, 2017, the US Environmental Protection Agency stated that it had reviewed close to 170 epidemiological, animal carcinogenicity and genotoxicity studies, and that the available data do not support a carcinogenic process for glyphosate (9).
- On April 28, 2017, Canada’s Pest Management Regulatory Agency (PMRA) reported in its completed re-evaluation of glyphosate that it is “unlikely to pose a human cancer risk.” In explaining why PMRA’s conclusions differed from those of IARC, PMRA stated “. . . the level of human exposure, which determines the actual risk, was not taken into account by IARC ” (10). PMRA renewed the registration of glyphosate in Canada with only minor label changes.
While both corn and soybean acreage AND yield have increased in Ontario since 1983, the overall environmental impact of herbicide use per acre has declined in large part because glyphosate has displaced other more harmful major herbicide chemistries.
This reduction in risk is due to 1) glyphosate being less hazardous, based on the EIQ, compared with these other herbicides, and 2) glyphosate being applied at a lower rate. Major regulatory agencies, such as Canada’s PMRA, have recently reconfirmed the safety of glyphosate and renewed its registration.
Glyphosate has played a key role in enabling many farmers to achieve excellent weed control in herbicide-tolerant crops while adopting reduced or zero tillage. This reduction in cultivation has positive implications for the environment in terms of soil health, water holding capacity and greenhouse gas balance.
Christopher P. Dufault is a Professional Agrologist, and the former head of the Re-evaluation and Use Analysis Section of the Pest Management Regulatory Agency in Canada. Currently, he is a Senior Agri-Coach with Agri-Trend and Principal of Christopher P. Dufault & Associates Inc., based in Ottawa, Ontario, Canada. Christopher.dufault(at)cantab.net. Robert Saik, a Professional Agrologist and Certified Agricultural Consultant, is the founder of Agri-Trend and Principal of Saik Management Group Inc., based in Olds, Alberta, Canada. Rob@RobertSAIK.com 403-391-0772. Neither has ever worked for any manufacturer of glyphosate.
- Farm & Food Care Ontario. 2015. Survey of Pesticide Use in Ontario, 2013/2014. Estimates of Pesticides Used on Field Crops and Fruit and Vegetable Crops. http://www.farmfoodcareon.org/wp- content/uploads/2016/10/ONTARIO-Pesticide- Use-Survey-Final-2013.pdf
- Duke, Stephen O. and Stephen B. Powles.2008. Mini-review. Glyphosate: a once-in-a-century herbicide. Pest Management Science. 64:319-325. https://naldc.nal.usda.gov/download/17918/PDF
- Brookes, Graham, Farzad Taheripour and Wallace E. Tyner. 2017. The contribution of glyphosate to agriculture and potential impact of restrictions on use at the global level. GM Crops & Food. Biotechnology in Agriculture and the Food Chain. 8: 4: 216-228. https://www.tandfonline.com/doi/full/10.1080/21645698.2017.1390637
- Van Eerd, Laura L. 2016. Environmental Risk of Pesticide Use in Ontario: 2013/2014 Pesticide Use Survey. http://www.farmfoodcareon.org/wp- content/uploads/2016/10/EIQSurvey2013FINAL.pdf
- Publication 75A Guide to Weed Control. Field Crops. 2018 [OMAFRA]. http://www.omafra.gov.on.ca/english/crops/pub75/pub75A/pub75A.pdf
- IARC Monographs Volume 112: evaluation of five organophosphate insecticides and herbicides. 2015 https://www.iarc.fr/en/media- centre/iarcnews/pdf/MonographVolume112.pdf
- Good Laboratory Practice (GLP). http://www.oecd.org/chemicalsafety/testing/go od-laboratory-practiceglp.htm
- Glyphosate not classified as a carcinogen by ECHA 2017 https://echa.europa.eu/-/glyphosate- not-classified-as-a-carcinogen-by-echa
- Revised Glyphosate Issue Paper. Evaluation of Carcinogenic Potential 2017. https://www.regulations.gov/document?D=EPA- HQ-OPP-2009-0361-0073
- Re-evaluation Decision RVD2017-01, Glyphosate. 2017. https://www.canada.ca/en/health- canada/services/consumer-product- safety/reports-publications/pesticides-pest- management/decisions-updates/registration- decision/2017/glyphosate-rvd-2017-01.html